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The Cox-2 Connection

Author: James B. LaValle

Publisher: Inner Traditions / Bear & Co

Published: 2001-09

Total Pages: 178

ISBN-13: 9780892819843

In this innovative text, James LaValle clearly explains what can cause joint and muscle inflammation, then sets forward mutliple treatments, with step-by-step instructions on how to use these treatments most effectively. Futhermore, he writes about exciting new studies that indicate the possible effectiveness of Cox-2 inhibitors in treating diseases such as cancer and Alzheimer's.

The Tumour Microenvironment

Author: Jamie A. Goode

Publisher: John Wiley & Sons

Published: 2001-11-28

Total Pages: 322

ISBN-13: 9780471499596

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Ergebnisse von in vitro-Studien lassen vermuten, dass sich der pH-Wert in einem Tumor auf die Wirksamkeit von Chemo- oder Strahlentherapien auswirken kann. Wie aber sieht die Beziehung zwischen der Tumorentwicklung und dem pH-Wert aus? Können ein niedriger pH-Wert oder ein Sauerstoffmangel die Carcinogenese hemmen? Wo bieten sich therapeutische Ansätze? Anwort auf diese und andere Fragen finden Sie in diesem Band. In interdisziplinärer Weise wurden Beiträge aus der Grundlagenforschung und der klinischen Praxis zusammengetragen.

The Essence of Analgesia and Analgesics

Author: Raymond S. Sinatra

Publisher: Cambridge University Press

Published: 2010-10-14

Total Pages: 551

ISBN-13: 1139491989

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The Essence of Analgesia and Analgesics is an invaluable practical resource for clinicians giving pain relief in any clinical setting, describing the pharmacologic principles and clinical use of all available pain medications. As well as detailed overviews of pain processing and analgesic theory, sections are dedicated to oral and panteral opioid analgesics, neuraxial opioids, NSAIDs, local anesthetics, anticonvulsant type analgesics, NMDA antagonists, alpha adrenergic analgesics, antidepressant analgesics, muscle relaxants, adjuvant medications, and new and emerging analgesics. The concise format of the chapters allows for quick and easy reading and assimilation of information. Enhanced by summary tables and figures, each chapter provides an overview of a particular drug, covering chemical structure, mode of activity, indications, contraindications, common doses and uses, advantages and disadvantages, and drug related adverse events. Key references are also provided. Edited by leading experts in pain management, this is essential reading for any clinician involved in pain management.

The Mind-Challenge Puzzle Book

Author: Emily Cox

Publisher: Sterling Publishing Company, Inc.

Published: 2002-12

Total Pages: 322

ISBN-13: 9781402704772

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Think ordinary conundrums are just too humdrum? Do you finish crossword puzzles in ink and in no time flat? Then get ready for a serious test of your skills, with the ultimate in mental challenges. We've got crosswords of course; more than 50 tough, "regular" ones. But you'll also enjoy dozens and dozens more of different varieties, including devilish "Crushwords" where you have to put more than one letter in each square, and mind-blowing math and logic teasers known as pixel puzzles, where if your answers are correct you'll create a picture of success! And if that isn't enough, you'll also find word puzzles that demand "lateral thinking," and may well be the truest test of your abilities.

Essential Clinical Anesthesia

Author: Charles Vacanti

Publisher: Cambridge University Press

Published: 2011-07-11

Total Pages: 1191

ISBN-13: 1139498401

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The clinical practice of anesthesia has undergone many advances in the past few years, making this the perfect time for a new state-of-the-art anesthesia textbook for practitioners and trainees. The goal of this book is to provide a modern, clinically focused textbook giving rapid access to comprehensive, succinct knowledge from experts in the field. All clinical topics of relevance to anesthesiology are organized into 29 sections consisting of more than 180 chapters. The print version contains 166 chapters that cover all of the essential clinical topics, while an additional 17 chapters on subjects of interest to the more advanced practitioner can be freely accessed at www.cambridge.org/vacanti. Newer techniques such as ultrasound nerve blocks, robotic surgery and transesophageal echocardiography are included, and numerous illustrations and tables assist the reader in rapidly assimilating key information. This authoritative text is edited by distinguished Harvard Medical School faculty, with contributors from many of the leading academic anesthesiology departments in the United States and an introduction from Dr S. R. Mallampati. This book is your essential companion when preparing for board review and recertification exams and in your daily clinical practice.

The Autoimmune Connection

Author: Rita Baron-Faust

Publisher: McGraw Hill Professional

Published: 2003-04-22

Total Pages: 427

ISBN-13: 0071425519

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Empowers women to make informed decisions about autoimmune disorders More than 50 million Americans, most of them women, suffer from a constellation of mysterious, often misdiagnosed diseases that can result in disability, disfigurement, and death. Called "autoimmune diseases," they arise when the immune system attacks healthy tissues in almost any area of the body, and include lupus rheumatoid arthritis, Crohn's disease, scleroderma, and Graves' disease. Now Jill Buyon, a doctor working on the cutting edge of research into these diseases, and Rita Baron-Faust, an award-winning medical journalist, arm women with the knowledge they need to obtain accurate diagnoses and the best possible treatments. In The Autoimmune Connection readers learn about the recent groundbreaking discovery of the links between the different autoimmune diseases and why women are more likely to develop them. The authors offer the most up-to-date information on diagnosis, treatments, and risks for women with one or more autoimmune disease.

Primes of the Form x2 + ny2

Author: David A. Cox

Publisher: John Wiley & Sons

Published: 2011-10-24

Total Pages: 372

ISBN-13: 1118031008

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Modern number theory began with the work of Euler and Gauss to understand and extend the many unsolved questions left behind by Fermat. In the course of their investigations, they uncovered new phenomena in need of explanation, which over time led to the discovery of field theory and its intimate connection with complex multiplication. While most texts concentrate on only the elementary or advanced aspects of this story, Primes of the Form x2 + ny2 begins with Fermat and explains how his work ultimately gave birth to quadratic reciprocity and the genus theory of quadratic forms. Further, the book shows how the results of Euler and Gauss can be fully understood only in the context of class field theory. Finally, in order to bring class field theory down to earth, the book explores some of the magnificent formulas of complex multiplication. The central theme of the book is the story of which primes p can be expressed in the form x2 + ny2. An incomplete answer is given using quadratic forms. A better though abstract answer comes from class field theory, and finally, a concrete answer is provided by complex multiplication. Along the way, the reader is introduced to some wonderful number theory. Numerous exercises and examples are included. The book is written to be enjoyed by readers with modest mathematical backgrounds. Chapter 1 uses basic number theory and abstract algebra, while chapters 2 and 3 require Galois theory and complex analysis, respectively.

Rift

Author: Richard Cox

Publisher: Ballantine Books

Published: 2004-06-29

Total Pages: 272

ISBN-13: 0345478487

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In an age where reality and science fiction are colliding, Richard Cox’s extraordinary debut thriller takes its place as an all-too-believable novel of white-knuckle adventure. For when an ordinary man makes one great leap for mankind, he triggers a chain of events that endangers his life, fractures his certainty, and plunges everyone he knows into a place where nothing is what it seems. Cameron Fisher is bored. With his wife, Misty. With his job as an accountant at NeuroStor, the high-tech microchip firm. With everything about his life—until he is offered five million dollars to test a secret new technology that uses a wrinkle in quantum physics to transmit matter from one place to another. His employer’s high-stakes brainchild is ready for its first human test. And Cameron Fisher is all too happy to oblige. One moment Cameron is sitting naked in a seven-by-seven-foot metal room in Houston; the next second he is in a laboratory in Phoenix—trembling now not with fear but joy. Within hours, Cameron will be free to go home. But first there is a celebratory drink—and a strange and scintillating meeting with a spectacularly beautiful woman. Then he’s being followed by men with guns . . . and suddenly Cameron is running, stumbling, falling into a world that looks like his own, but in which he has become a ragged stranger, accused of murder and pursued by people who want him dead. It appears that NeuroStor’s invention has changed Cameron. Next, it will change the entire world. With its stunning twists, sensual adventure, and raw, psychological suspense, Rift takes readers on a thrill-a-second ride to one last amazing choice for Cameron Fisher. A gripping and utterly satisfying work of storytelling magic, Rift asks the ultimate question: What if you had to die to find out what it really means to be alive?

An Introduction to 5G

Author: Christopher Cox

Publisher: John Wiley & Sons

Published: 2020-12-14

Total Pages: 452

ISBN-13: 1119602661

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A comprehensive and approachable introduction to 5G Written by a noted expert on the subject, An Introduction to 5G: The New Radio, 5G Network and Beyond offers an introductory system-level guide to 5G. The material covered includes: The use cases and requirements of the 5G system The architecture of the next generation radio access network and the 5G core The principles of radio transmission, millimetre waves and MIMO antennas The architecture and detailed design of the 5G new radio The implementation of HTTP/2 on the service-based interfaces of the 5G core The signalling procedures that govern the end-to-end-operation of the system The new features that are introduced in Releases 16 and 17 An Introduction to 5G is written for engineering professionals in mobile telecommunications, for those in non-technical roles such as management, marketing and intellectual property, and for students. It requires no more than a basic understanding of mobile communications, and includes detailed references to the underlying 3GPP specifications for 5G. The book's approach provides a comprehensive, end-to-end overview of the 5G standard, which enables readers to move on with confidence to the more specialized texts and to the specifications themselves.

Immunotherapy of Hepatocellular Carcinoma

Author: Tim F. Greten

Publisher: Springer

Published: 2017-10-04

Total Pages: 167

ISBN-13: 3319649582

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In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.