Viruses

Viruses PDF

Author: Dorothy H. Crawford

Publisher: Oxford University Press

Published: 2018

Total Pages: 177

ISBN-13: 0198811713

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Viruses are big news. From pandemics such as HIV, swine flu, and SARS, we are constantly being bombarded with information about new lethal infections. In this Very Short Introduction, Dorothy Crawford demonstrates from their discovery and the unravelling of their intricate structures, how clever these entities really are.

Viruses: A Very Short Introduction

Viruses: A Very Short Introduction PDF

Author: Dorothy H. Crawford

Publisher: OUP Oxford

Published: 2011-07-28

Total Pages: 176

ISBN-13: 0191620432

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Viruses are big news. From pandemics such as HIV, swine flu, and SARS, we are constantly being bombarded with information about new lethal infections. In this Very Short Introduction Dorothy Crawford demonstrates how clever these entities really are. From their discovery and the unravelling of their intricate structures, Crawford demonstrates how these tiny parasites are by far the most abundant life forms on the planet. With up to two billion of them in each litre of sea water, viruses play a vital role in controlling the marine environment and are essential to the ocean's delicate ecosystem. Analyzing the threat of emerging virus infections, Crawford recounts stories of renowned killer viruses such as Ebola and rabies as well as the less known bat-borne Nipah and Hendra viruses. Pinpointing wild animals as the source of the most recent pandemics, she discusses the reasons behind the present increase in potentially fatal infections, as well as evidence suggesting that long term viruses can eventually lead to cancer. By examining our lifestyle in the 21st century, Crawford looks to the future to ask whether we can ever live in harmony with viruses, and considers the ways in which we may need to adapt to prevent emerging viruses with devastating consequences. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Viruses

Viruses PDF

Author: Dorothy H. Crawford

Publisher: Oxford University Press

Published: 2021-10-28

Total Pages: 273

ISBN-13: 0192659529

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For all our hubris, humans can be felled rapidly by an invisible enemy - viruses. All around us are minute entities that can damage and kill: the millions of viruses that pervade the natural world. Our bodies harbour many that we have long tolerated, but a new one, that jumps into humans from another species, can be lethal - as we have seen most recently with the virus responsible for COVID-19. But what are viruses, how do they cause disease, and how can we fight them? In Viruses: The Invisible Enemy, a brand new edition of her classic work, virologist Dorothy Crawford explores these questions. She takes the reader on a journey through the past to show how, as the human race evolved from hunter gatherer to farmer to our present urban, industrialised society, viruses have taken advantage of each lifestyle change to promote their own survival. We have acquired many new viruses along the way, some spreading globally and causing killer diseases. But now, in the 21st century, as humans increasingly encroach into and exploit the natural world, the rate of emergence of novel viruses is accelerating. Already we've had a flu pandemic, large epidemics from SARS, Ebola and Zika viruses, and most devastating of all, SARS-CoV-2, which swept around the world in 2020-21, causing the COVID-19 pandemic. The response of scientists has been rapid, producing vaccines in record time. But we can expect more such challenges in the future. This book discusses why and how SARS-CoV-2 and other killer viruses emerged, and how we can win the battle against such an enemy.

Marine Biology: a Very Short Introduction

Marine Biology: a Very Short Introduction PDF

Author: Philip Mladenov

Publisher: Oxford University Press, USA

Published: 2020-02-27

Total Pages: 225

ISBN-13: 019884171X

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The oceans are our planet's most distinctive and imposing natural habitat. They cover 71 percent of its surface; support a remarkably diverse and exquisitely adapted array of life forms, from microscopic viruses, bacteria, and plankton to the largest existing animals; and possess many of Earth's most significant, intriguing, and inaccessible ecosystems. In an era in which humans are significantly altering the global environment, the oceans are undergoing rapid and profound changes. The study of marine biology is thus taking on added importance and urgency as people struggle to understand and manage these changes to protect our marine ecosystems. Healthy oceans produce half of the oxygen we breathe; stabilize our climate; create ecosystems that protect our coasts from storms; provide us with abundant food; and host diverse organisms that provide us with natural products for medicine and biotechnology. In this Very Short Introduction, marine biologist Philip Mladenov provides an accessible and up-to-date overview of marine biology, offering a tour of marine life and marine processes that ranges from the unimaginably abundant microscopic organisms that drive the oceans' food web to the apex predators that we exploit for food; from polar ocean ecosystems to tropical coral reefs; and from the luxurious kelp beds of the coastal ocean to deep-ocean hydrothermal vents where life exists without the energy of the sun. Throughout the book he considers the human impacts on marine life including overfishing, plastic and nutrient pollution, the spread of exotic species, and ocean warming and acidification. He discusses the threats these pose to our welfare, and the actions required to put us on a path to a more sustainable relationship with our oceans so that they can be restored and protected for future generations. Mladenov concludes with a new chapter offering an inspiring vision for the future of our oceans in 2050 that can be realised if we are wise enough to accelerate actions already underway and be bold with implementing new approaches. The next decade will decide the state of the oceans that we leave behind for future generations. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Viruses, Plagues, and History

Viruses, Plagues, and History PDF

Author: Michael B. A. Oldstone

Publisher: Oxford University Press, USA

Published: 2020

Total Pages: 513

ISBN-13: 0190056789

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"Here, my previous edition of Viruses, Plagues, & History is updated to reflect both progress and disappointment since that publication. This edition describes newcomers to the range of human infections, specifically, plagues that play important roles in this 21st century. The first is Middle East Respiratory Syndrome (MERS), an infection related to Sudden Acute Respiratory Syndrome (SARS). SARS was the first new-found plague of this century. Zika virus, which is similar to yellow fever virus in being transmitted by mosquitos, is another of the recent scourges. Zika appearing for the first time in the Americas is associated with birth defects and a paralytic condition in adults. Lastly, illness due to hepatitis viruses were observed prominently during the second World War initially associated with blood transfusions and vaccine inoculations. Since then, hepatitis virus infections have afflicted millions of individuals, in some leading to an acute fulminating liver disease or more often to a life-long persistent infection. A subset of those infected has developed liver cancer. However, in a triumph of medical treatments for infectious diseases, pharmaceuticals have been developed whose use virtually eliminates such maladies. For example, Hepatitis C virus infection has been eliminated from almost all (>97%) of its victims. This incredible result was the by-product of basic research in virology as well as cell and molecular biology during which intelligent drugs were designed to block events in the hepatitis virus life-cycle"--

Genomics: A Very Short Introduction

Genomics: A Very Short Introduction PDF

Author: John M. Archibald

Publisher: Oxford University Press

Published: 2018-02-22

Total Pages: 144

ISBN-13: 0191089478

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Genomics has transformed the biological sciences. From epidemiology and medicine to evolution and forensics, the ability to determine an organism's complete genetic makeup has changed the way science is done and the questions that can be asked of it. Its most celebrated achievement was the Human Genome Project, a technologically challenging endeavor that took thousands of scientists around the world 13 years and over 3 billion US dollars to complete. In this Very Short Introduction John Archibald explores the science of genomics and its rapidly expanding toolbox. Sequencing a human genome now takes only a few days and costs as little as $1,000. The genomes of simple bacteria and viruses can be sequenced in a matter of hours on a device that fits in the palm of your hand. The resulting sequences can be used to better understand our biology in health and disease and to 'personalize' medicine. Archibald shows how the field of genomics is on the cusp of another quantum leap; the implications for science and society are profound. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Infectious Disease

Infectious Disease PDF

Author: Marta L. Wayne

Publisher: Oxford University Press, USA

Published: 2015

Total Pages: 137

ISBN-13: 0199688931

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A Very Short Introduction considers where particular diseases come from, how they are transmitted from one person to another, why some individuals are more susceptible than others, and what strategies can be used to combat these diseases. It explains the general principles of infection, the management of outbreaks, and the evolutionary and ecological approaches that are now central to much research about infectious disease.

The Immune System

The Immune System PDF

Author: Paul Klenerman

Publisher: Oxford University Press

Published: 2017

Total Pages: 145

ISBN-13: 019875390X

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The immune system is central to human health and the focus of much medical research. Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine. In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behavior, and the major health threats where it is important. The immune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called innate immune responses, which react very fast to infection, and adaptive immune responses, which have huge diversity and a capacity to recognize and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading to serious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the Immune system v2.o - how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

A Planet of Viruses

A Planet of Viruses PDF

Author: Carl Zimmer

Publisher: University of Chicago Press

Published: 2015-10-06

Total Pages: 133

ISBN-13: 022632026X

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For years, scientists have been warning us that a pandemic was all but inevitable. Now it's here, and the rest of us have a lot to learn. Fortunately, science writer Carl Zimmer is here to guide us. In this compact volume, he tells the story of how the smallest living things known to science can bring an entire planet of people to a halt--and what we can learn from how we've defeated them in the past. Planet of Viruses covers such threats as Ebola, MERS, and chikungunya virus; tells about recent scientific discoveries, such as a hundred-million-year-old virus that infected the common ancestor of armadillos, elephants, and humans; and shares new findings that show why climate change may lead to even deadlier outbreaks. Zimmer’s lucid explanations and fascinating stories demonstrate how deeply humans and viruses are intertwined. Viruses helped give rise to the first life-forms, are responsible for many of our most devastating diseases, and will continue to control our fate for centuries. Thoroughly readable, and, for all its honesty about the threats, as reassuring as it is frightening, A Planet of Viruses is a fascinating tour of a world we all need to better understand.

Epidemiology: A Very Short Introduction

Epidemiology: A Very Short Introduction PDF

Author: Rodolfo Saracci

Publisher: OUP Oxford

Published: 2010-02-25

Total Pages: 160

ISBN-13: 0191609242

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What is epidemiology? What are the causes of a new disease? How can pandemics be prevented? Epidemiology is the study of the changing patterns of disease and its main aim is to improve the health of populations. It's a vital field, central to the health of society, to the identification of causes of disease, and to their management and prevention. Epidemiology has had an impact on many areas of medicine; from discovering the relationship between tobacco smoking and lung cancer, to the origin and spread of new epidemics. However, it is often poorly understood, largely due to misrepresentations in the media. In this Very Short Introduction Rodolfo Saracci dispels some of the myths surrounding the study of epidemiology. He provides a general explanation of the principles behind clinical trials, and explains the nature of basic statistics concerning disease. He also looks at the ethical and political issues related to obtaining and using information concerning patients, and trials involving placebos. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.