The Agonist

The Agonist PDF

Author: Shastra Deo

Publisher: Uqp Poetry

Published: 2017

Total Pages: 0

ISBN-13: 9780702259746

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Winner of the 2016 Thomas Shapcott Prize for Poetry.

Principles of Biomedical Sciences and Industry

Principles of Biomedical Sciences and Industry PDF

Author: Markus Hinder

Publisher: John Wiley & Sons

Published: 2022-07-22

Total Pages: 452

ISBN-13: 3527824006

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Principles of Biomedical Sciences and Industry Improve your product development skills to bring new ideas to biomedicine The development of innovative healthcare products, such as biodegradable implants, biopharmaceuticals, or companion diagnostics, requires a multi-disciplinary approach that incorporates scientific evidence with novel and innovative ideas to create new and improved products and treatments. Indeed, product development and the integration of science with commercial aspects have become key challenges for scientists working in the pharmaceutical, biotech, and medtech industries. Using a multi-pronged approach to development, Principles of Biomedical Sciences and Industry combines ideas and methodologies from four of the central areas of focus in the biomedical arena: pharmaceuticals, diagnostics, biomaterials, and medical devices. In doing so, the book covers the entire product lifecycle, from translating a scientific idea into a prototype to product development, launch, and management. Principles of Biomedical Sciences and Industry readers will also find: Several case studies from the most important product categories (pharmaceuticals, diagnostics, medical devices, combination products) Chapters dealing with toxicology and safety risks in development, as well as regulatory approval Key business aspects including how to secure funding, managing intellectual property, and price regulation in the market An ideal resource for teachers and students that conveys the information in an easily-digestible format Ideal for advanced students and young professionals pursuing a career in the biomedical and healthcare industries, Principles of Biomedical Sciences and Industry is an essential reference for those in pharmaceutical industry, biotechnologists, medicinal chemists, bio-engineers, pharma engineers, and management consultants.

Anatomy ;Ocular physiology ;Biochemistry and genetics ;Pathology ;Microbiology ;Immunology ;Growth and senescence ;Optics ;Therapeutics ;Lasers and instrument technology ;Basic biostatistical and epidemiological terms

Anatomy ;Ocular physiology ;Biochemistry and genetics ;Pathology ;Microbiology ;Immunology ;Growth and senescence ;Optics ;Therapeutics ;Lasers and instrument technology ;Basic biostatistical and epidemiological terms PDF

Author: Louise Bye

Publisher: OUP Oxford

Published: 2013-05-23

Total Pages: 285

ISBN-13: 0199584990

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An indispensable and fully comprehensive textbook, this covers the basic sciences in ophthalmology and is the only book you need to pass the FRCOphth Part 1 exam.

The forbid/allow asymmetry

The forbid/allow asymmetry PDF

Author: Bregje Holleman

Publisher: BRILL

Published: 2021-09-13

Total Pages: 258

ISBN-13: 9004489371

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Questionnaires are widely used in the social sciences and very often survey data form the basis for governmental and commercial planning or evaluation. Yet the quality of survey data is not attested to, since a large variety of factors in the language-use situation prove to influence the answers unintentionally. The forbid/allow asymmetry is a well-known example of this: when respondents are asked whether something should be forbidden, about 50% may answer ‘yes, forbid’ – whereas an equivalent question phrased with the verb ‘to allow’ could well cause up to 75% of the respondents to answer ‘no, it should not be allowed’. Which question wording is preferable to measure respondents’ true attitudes? Only when we know why the answers differ, can we decide on that. This book is the first to apply a systematic cognitive approach to describe the causes of the forbid/allow asymmetry. The question-answering process is unravelled by a variety of experiments and meta-analytic techniques. Analyses reveal that the difference in question wording does not prompt respondents to retrieve different attitudes. Instead, the asymmetry reflects that the question wording causes the response options to be used differently. Because of the qualifying dimensions in the question text, the meanings of ‘yes’ and ‘no’ change, as well as the cognitive distance between them. This study sheds a different light on processes of question-answering and text interpretation. Furthermore, practical advice on questionnaire design and on the interpretation of survey data is given on the basis of these new insights.

Mathematical Physiology

Mathematical Physiology PDF

Author: James Keener

Publisher: Springer Science & Business Media

Published: 2010-06-04

Total Pages: 547

ISBN-13: 038775847X

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Divided into two volumes, the book begins with a pedagogical presentation of some of the basic theory, with chapters on biochemical reactions, diffusion, excitability, wave propagation and cellular homeostasis. The second, more extensive part discusses particular physiological systems, with chapters on calcium dynamics, bursting oscillations and secretion, cardiac cells, muscles, intercellular communication, the circulatory system, the immune system, wound healing, the respiratory system, the visual system, hormone physiology, renal physiology, digestion, the visual system and hearing. New chapters on Calcium Dynamics, Neuroendocrine Cells and Regulation of Cell Function have been included. Reviews from first edition: Keener and Sneyd's Mathematical Physiology is the first comprehensive text of its kind that deals exclusively with the interplay between mathematics and physiology. Writing a book like this is an audacious act! -Society of Mathematical Biology Keener and Sneyd's is unique in that it attempts to present one of the most important subfields of biology and medicine, physiology, in terms of mathematical "language", rather than organizing materials around mathematical methodology. -SIAM review

Multiple Muscle Systems

Multiple Muscle Systems PDF

Author: Jack M. Winters

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 818

ISBN-13: 1461390303

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The picture on the front cover of this book depicts a young man pulling a fishnet, a task of practical relevance for many centuries. It is a complex task, involving load transmission throughout the body, intricate balance, and eye head-hand coordination. The quest toward understanding how we perform such tasks with skill and grace, often in the presence of unpredictable pertur bations, has a long history. However, despite a history of magnificent sculptures and drawings of the human body which vividly depict muscle ac tivity and interaction, until more recent times our state of knowledge of human movement was rather primitive. During the past century this has changed; we now have developed a considerable database regarding the com position and basic properties of muscle and nerve tissue and the basic causal relations between neural function and biomechanical movement. Over the last few decades we have also seen an increased appreciation of the impor tance of musculoskeletal biomechanics: the neuromotor system must control movement within a world governed by mechanical laws. We have now col lected quantitative data for a wealth of human movements. Our capacity to understand the data we collect has been enhanced by our continually evolving modeling capabilities and by the availability of computational power. What have we learned? This book is designed to help synthesize our current knowledge regarding the role of muscles in human movement. The study of human movement is not a mature discipline.

Clinical Pharmacology and Poisoning

Clinical Pharmacology and Poisoning PDF

Author: Derek G. Waller

Publisher: Elsevier Health Sciences

Published: 2016-09-13

Total Pages:

ISBN-13: 0702071218

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Clinical Pharmacology and Poisoning is a new e-book in a collection of subject-themed e-books containing relevant key articles from Medicine. The e-books provide a perfect source of revision for post-graduate exams in clinical medicine and portfolio material for life-long learning. As well as mapping to the UK Core Medical Training curriculum, these e-books also enable anyone with a short-term interest in a specific area to buy individual articles at a price-point that will give affordable access to all readers (from medical students to GPs and practitioners in related areas). The quality of user experience on mobiles, tablets and laptops will be an added bonus for learning on the move. The whole board has been involved in the creation of this content and are therefore listed as authors on all the e-books. In addition we extend our warm thanks for their contribution to these e-books to the past Chairman Allister Vale (who stepped down from the board in 2015) and to John Mucklow, who stepped down in 2016. Derek Waller, on behalf of the Editorial Board About the journal The parent journal (www.medicinejournal.co.uk) is a rolling, continuously updated review of clinical medicine over a 4-year cycle covering all the important topics for core medical training. Its Editorial Board comprises some of Europe’s most influential specialists. The journal’s articles are refreshed, updated, augmented or replaced as appropriate each time the subject is due for revision to provide a concise overview of knowledge and practice core to the curriculum. Each article is written by invited experts and overseen by the relevant subject specialist on the Board. A trainee representative on the Board ensures relevance and accessibility for exam candidates. About the Medicine journal e-books Clinical Pharmacology and Poisoning is a new e-book in a collection of subject-themed e-books containing relevant key articles from Medicine. The e-books provide a perfect source of revision for post-graduate exams in clinical medicine and portfolio material for life-long learning. As well as mapping to the UK Core Medical Training curriculum, these e-books also enable anyone with a short-term interest in a specific area to buy individual articles at a price-point that will give affordable access to all readers (from medical students to GPs and practitioners in related areas). The quality of user experience on mobiles, tablets and laptops will be an added bonus for learning on the move. The whole board has been involved in the creation of this content and are therefore listed as authors on all the e-books. In addition we extend our warm thanks for their contribution to these e-books to the past Chairman Allister Vale (who stepped down from the board in 2015) and to John Mucklow, who stepped down in 2016. Derek Waller, on behalf of the Editorial Board About the journal The parent journal (www.medicinejournal.co.uk) is a rolling, continuously updated review of clinical medicine over a 4-year cycle covering all the important topics for core medical training. Its Editorial Board comprises some of Europe’s most influential specialists. The journal’s articles are refreshed, updated, augmented or replaced as appropriate each time the subject is due for revision to provide a concise overview of knowledge and practice core to the curriculum. Each article is written by invited experts and overseen by the relevant subject specialist on the Board. A trainee representative on the Board ensures relevance and accessibility for exam candidates.

The Cerebellum, Epilepsy, and Behavior

The Cerebellum, Epilepsy, and Behavior PDF

Author: Irving Cooper

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 402

ISBN-13: 1461345081

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In cats anesthetized lightly with pentobarbital or alpha-chloralose, electrical stimulation of the paramedian lobule of cerebellum resulted in a change of EEG pattern. Prior to stimulation the pattern consisted of h igh-ampl itude slow waves with superimposed low-ampl itude fast activity. In addition, the EEGs of animals anesthetized with chloralose showed "chloralose spikes". Immediately following brief cerebellar stimulation the slow wave activity and spikes disappeared, leaving only low-voltage fast activity. The effect was most pronounced in the contralateral leads from the rostral portions of the cerebrum. Study of the parameters most effective in evoking this effect revealed that stimulation frequency, train duration, and probably pulse duration affected the duration of suppression in a sigmoid fashion, with inflection points at approximately 90 Hz, 2.5 sec, and 1 msec, respectively. Above threshold values, stimulation cur rent showed an approximately linear relationship to duration of EEG sup pression. The after-discharge resulting from focal electrical stimulation of the cerebral cortex could be shortened by electrical stimulation of the para median lobule. The effect was essentially the same when cerebellar stim ulation preceded, occurred during, or followed the cerebral cortical stim ulation. The great variability of the after-discharge resulting from cerebral cortical stimulation as well as the variability of the effects of cerebellar stimulation made it impractical to study systematically the parameters op timal for shorten ing after-discharge. Such a study wi II require use of an awake, preferably partially restrained animal with electrodes chronically implanted.

Pharmacology E-Book

Pharmacology E-Book PDF

Author: George M. Brenner

Publisher: Elsevier Health Sciences

Published: 2012-11-14

Total Pages: 530

ISBN-13: 1455702781

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Pharmacology, 4th Edition helps you master the "must-know" concepts in this subject and how they apply to everyday clinical problem solving and decision making. This concise yet comprehensive text clearly explains and illustrates challenging concepts and helps you retain the material - from course exams and the USMLE Step 1 right through to clinical practice. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Quickly reference essential information thanks to abundant tables throughout, and drug classification boxes at the beginning of each chapter. See how pharmacology applies to practice with real-world case studies. Prepare for exams with self-assessment questions at the end of each chapter. Understand complex concepts visually with the aid of superb full-color illustrations. Access the complete contents online at www.studentconsult.com, along with an additional glossary, chapter-by-chapter summaries and case studies, a full list of featured drugs, 150 USMLE-style questions, animations, and more. Learn the latest pharmacologic mechanisms and applications with new and updated drug information throughout. Be aware of new "off label" uses, including important FDA regulations.

Metaphors of Coronavirus

Metaphors of Coronavirus PDF

Author: Jonathan Charteris-Black

Publisher: Springer Nature

Published: 2021-11-12

Total Pages: 308

ISBN-13: 3030851060

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This book explores the metaphors used in public and media communication to ask how language shapes our moral reasoning about the global coronavirus crisis. The author offers insights into the metaphors, metonyms, allegories and symbols of the global crisis and examines how they have contributed to policy formation and communication. Combining metaphor theory with moral foundations theory, he places metaphors in their historical contexts, and then critically questions why certain tropes might be used in particular situations to persuade and convince an audience. The book takes an integrated approach, involving ideas from cognitive linguistics, history, social psychology and literature to produce a multi-layered and thematically rich interpretation of the language of the pandemic and its social and political consequences. It will be relevant to readers with a background in these areas, as well as anyone with a general interest in the language used to make sense of this global event.